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Posts with tag bone

Meg Wolff blogs about a life in balance

Meg Wolff survived cancer -- twice. First she had bone cancer and lost her leg to the disease. Then she had breast cancer and was given little hope from doctors who thought traditional treatment could not save her. Maybe it couldn't. But Wolff found something that did save her -- a macrobiotic diet.

Life is all about balance, says Wolff who authors a website rich in content about the connection between diet and a healthy lifestyle. She offers up-to-date information on her blog, links to recipes and resources, a calendar of events, and a look at her very own book, titled, Becoming Whole, The Story of My Complete Recovery from Breast Cancer.

Wolff says that by changing her diet, she has changed her destiny. She is alive and well and thriving. Give her a visit and see for yourself.

LBBC teleconference: Bone Health After Breast Cancer

Join Living Beyond Breast Cancer for the next national teleconference, Bone Health After Breast Cancer, from 12:00 p.m. to 1:30 p.m. Eastern Daylight Time (EDT) on Tuesday, September 11.

Adam Brufsky, MD, PhD, of the University of Pittsburgh School of Medicine, will give an overview of the topic of bone health for women after breast cancer diagnosis, including:

  • Causes of bone loss
  • How to measure bone health
  • How breast cancer treatment impacts bone loss
  • Strategies for monitoring bone health before and after treatment
  • Using exercise, fitness and supplements to keep bones strong
  • Bone-strengthening medications

Continue reading LBBC teleconference: Bone Health After Breast Cancer

Cancer by the Numbers: Osteosarcoma

Overview of osteosarcoma:

There are about 900 new cases of osteosarcoma diagnosed in the US each year. About 400 occur in children and adolescents younger than 20 years of age.

Osteosarcoma forms in the bones. It is most commonly diagnosed in those who are 15 to 25 years of age. It is also the most common type of bone cancer, and the sixth most common type of cancer in children.

Other types of cancer can eventually metastasize to the bone, however this disease originates in the bone and can spread elsewhere to other parts of the body.

Many cases of osteosarcoma, around 80 percent, begin in or around the knee area.

What are the risks of osteosarcoma?

The disease is most seen in boys and can arise from unpredictable errors in the DNA of growing bone cells during times of intense bone growth. Currently, there is no effective way to prevent this type of cancer but with proper treatment most kids diagnosed with osteosarcoma do recover.

Continue reading Cancer by the Numbers: Osteosarcoma

Know the signs and symptoms of myeloma

The American Cancer Society estimates that approximately 16,600 new cases of myeloma are diagnosed each year in the United States. Bone pain is the most common early symptom of myeloma. Most patients feel pain in their back or ribs, but it can occur in any bone. The pain is usually made worse by movement.

Patients fatigue more easily and often feel weak. They may also have a pale complexion from anemia which is a common medical problem for patients with myeloma and may contribute to the fatigue. If the disease progresses, the concentration of normal cells in the blood may also decrease. Headaches, bruising, nose bleeding, gastrointestinal bleeding, and tingling or numbness in extremities are all symptoms of myeloma.

Patients may have repeated infections because antibodies to invading viruses, bacteria or other disease agents are not made efficiently of in adequate amounts. Urinary tract, bronchial, lung, skin, or other sites of infection may be the first sign of the disease. In addition, recurrent infections may complicate the course of the disease.

TV's Mr. Wizard Don Herbert dies of bone cancer

Don Herbert, also known as television's science teacher Mr.Wizard, died at his home Tuesday of bone cancer. He was 89.

Mr. Wizard's target audience was kids (baby boomers: you may already know this) and his lessons taught youngsters to use the thinking skills of scientists through workshop experiments using simple household items. His 1950s series Watch Mr. Wizard was so good it won a Peabody Award in 1954, and Herbert was one of David Letterman' first guests when the show Late Night With David Letterman debuted in 1982. Herbert's show made it to Nickelodeon too and ran from 1983 to 1991. Reruns were shown until 2000. Nickelodeon's Mr. Wizard episodes are available here.

A native of Waconia, Minnesota, Herbert graduated from LaCrosse State Teachers College in 1940; served as a U.S. Army Air Corps pilot during World War II; and worked as an actor, model, and radio writer before reaching fame on Mr. Wizard in Chicago -- and then New York -- on NBC.

He is survived by six children and stepchildren and by his second wife, Norma.

Stem cells may look, but not act, like cancer

I love it when I find research coming straight from the halls of the very hospital where I received my breast cancer treatment. It reminds me that I'm in good hands, that University of Florida researchers are on the cusp of breaking through the mysteries of cancer, that I may one day be the lucky recipient of cutting-edge discoveries, like this:

University of Florida researchers report in a paper to be published in the August issue of Stem Cells that bone marrow stem cells attracted to the site of cancerous growths often take on the appearance of the malignant cells surrounding them. While these cells look like cancer, though, they may not act like cancer. They have the same skin, says lead study author Dr. Chris Cogle. But the question is: do they have the same guts?

"Our results indicate these cells act as developmental mimics; they come in and look like the surrounding neoplastic tissue, but they aren't actually the seed of cancer," said Cogle who is affiliated with the cancer center I've called home for more than two years.

Continue reading Stem cells may look, but not act, like cancer

Thought for the Day: Chinese herbs to the rescue

I've always heard the use of herbs and supplements and alternative therapies can be a potentially dangerous pursuit when combined with cancer treatment. But this may not be entirely true.

Think about this:

Using Chinese herbs alone or in conjunction with chemotherapy may help protect a breast cancer patient's bone marrow and immune system. It may also improve the overall quality of life for women, say researchers at the Chinese Cochrane Centre in Chengdu, China.

It is well known that women receiving chemotherapy for breast cancer experience significant short term side effects such as nausea, vomiting, fatigue, inflammation of the gut lining, decreased numbers of red and white blood cells, and decreased numbers of blood platelets. Those is search of some relief may wish to give Chinese medicinal herbs a try.

Researchers say there is conventional evidence indicating that these medicines are safe and effective. Still, "further trials are needed before the effects of traditional Chinese medicines for people with breast cancer can be evaluated with any real confidence," says one professor involved in this area of study.

Working through cancer treatments

In the news there has been a lot of questioning whether or not it is wise for someone diagnosed with cancer, and needs therapy or treatments to control their cancer, should still work or carry on with their life the way it was before cancer entered into their lives.

Its a good question -- but all cancer survivors or patients must make this decision themselves and should not be judged either way. Treatments can be physically mild or debilitating and everywhere in between.

I know women who are walking in Elizabeth Edward's shoes and have metastatic breast cancer. These women that I know might not be blazing the campaign trail but they are still keepin-on- keepin-on with life like it was before their breast cancer returned. They still get up and go to work, do the laundry, feed their children, all the normal things that you and I do everyday. Not to say that days can't be really tough, emotionally and physically. But I see women who are living with the disease -- really living and not giving up any of their dreams.

I can't really speak for women with metastatic disease, I can only talk about what I see, because I am not walking in their shoes and don't completely understand what it is like living with recurrent breast cancer.

Recurrent breast cancer can mean being on some kind of cancer treatment for the rest of your life, it can mean long times of remission or no evidence of disease.

Can it mean Elizabeth Edwards being first lady with metastatic breast disease? I think so.

Stem cells used to regenerate liver tissue

In the April issue of the journal Radiology, researchers published a report that says they have used adult bone marrow stem cells to regenerate healthy human liver tissue.

When cancer invades the liver sometimes it is impossible to have surgery performed to remove the tumor. This is because there is not enough healthy liver left behind to support the body. These stems cells help to regenerate the healthy portion of the liver so surgery can be performed.

Gunther Furst, M.D, coauthor and professor of radiology, says "Our study suggests that liver stem cells harvested from the patients own bone marrow can further augment and accelerate the liver's natural capacity to regenerate itself."

Fosamax prevents bone loss in prostate cancer patients

Hormonal therapy for prostate cancer can cause many side effects, one being bone loss. The goal of the hormonal therapy is to reduce the levels of the male hormones, called androgens, in the body. The main androgen is testosterone. Androgens can stimulate prostate cells to grow and lowering the levels often makes prostate cancer cells shrink or grow more slowly.

The Annals of Internal Medicine published an article that says Fosamax (alendronate) can prevent and even reverse bone loss associated with hormonal treatment for prostate cancer.

A trial was conducted that showed after one year bone density had increased among patients treated with Fosamax but had decreased among patients who received a placebo.

If you are receiving hormonal treatment for prostate cancer ask your doctor about a bisphosphonate, like Fosamax to control bone loss.

Cancer 'hot Spot' found in Elizabeth Edwards' hip

Ever since revealing her breast cancer had recurred, there has been speculation about a spread from Elizabeth Edwards' rib -- the initial metastasis -- to other spots in her body.

Last night, on the CBS news program 60 Minutes, Edwards told Katie Couric that a hot spot has been detected in her right hip. But doctors believe it is too small to pose a new health risk, she reports.

"There are a couple of hot spots, on the bone scan, in my right hip, for example," she said. "And one of the questions is whether or not to do radiation to reduce the size of that -- of the cancer in that location -- and for fear that it might weaken my bone and that I might break my hip. But their consensus was that it was too small an area for that to be a risk."

In addition to discussion about the cancer itself, Edwards and her husband John defended their decision to stick with the presidential race. Edwards said she just cannot deny her husband the chance to be president.

"That would be my legacy, wouldn't it, Katie?" Edwards said to Couric. "That I'd taken out this fine man from -- from the possibility of -- of giving a great service. I mean, I don't want that to be my legacy."

John Edwards wife Elizabeth has recurrence of breast cancer

I just finished watching the press conference held by John Edwards and Elizabeth Edwards. Elizabeth stated that she had some tests earlier in the week that confirmed her breast cancer has metastasized to the bone.

John and Elizabeth said they will continue on with their campaign -- they seemed to have a very positive attitude. They are happy that the cancer is confined to the bone and has not spread to other organs in her body.

Being a breast cancer survivor, I know women who have been diagnosed with advanced disease. Many are living fulfilling lives even though they must always be on some form of treatment. At this day and age advanced breast cancer cannot be cured but can be successfully treated. There are many therapies available for Elizabeth.

I applaud her courage -- Elizabeth said "she wants to live next week the same way she lived last week." Its easy to crawl up in a ball, getting a Stage IV diagnosis is hard to take. Her husband said that no matter where he is or what he is doing he will be there for Elizabeth whenever she needs him.

Zometa and Aredia go head to head to treat bone mets

Bisphosphonates are medicines that help build bone mineral density and strengthen bone. When breast cancer travels to the bone, it can weaken them and may cause them to become brittle.

A Phase III study has reported that two years after starting bisphosphonate treatment, women who took Zometa went longer without bone difficulties that those who took Aredia.

The study compared the effectiveness of the two bisphosphonate medications to see which worked better when given over a two year period. The results, after 13 months, showed Zometa did better than Aredia at reducing overall risk of weakening, pain or fracture of bone.

The two year results showed that those who were treated with Zometa had a 45 percent average reduction annually in the number of bone weakening, pain or fractures compared to Aredia.

The most important part is what this can mean for you -- This study suggests that Zometa may be a viable long-term option for women with ER+ advanced breast cancer to the bone. If you have ER- disease, this study suggests you may receive an equally good result from Zometa or Aredia.

Bone loss halted in breast cancer patients treated with Risedronate

The January issue of The Journal of Clinical Endocrinology & Metabolism reported that once a week treatment with Risedronate prevents bone loss in breast cancer patients who underwent treatment with chemotherapy.

Risedronate, a bisphosphonate used to strengthen the bone, is shown to increase bone mineral density (BMD) in the spine by 1.2% after one year of treatment. Markers of bone resorption decreased significantly in the treatment group compared with the placebo group.

The authors noted "These results have important clinical ramifications for breast cancer survivors who go into remission after aggressive therapy. Because of the long-term survival of this cohort, they are at risk for bone loss and osteoporosis. Skeletal integrity needs to be assessed and considered as part of their long-term management."

Some other topics on The Cancer Blog concerning bisphosphonates:

Premenopausal breast cancer patients and bone loss

Postmenopausal Breast Cancer Survivors at Risk for Osteoporosis

Sunshine in the forecast for skin cancer prevention

Way back in my sun worshipping days -- when I longed for a golden tan, logged countless hours scorching my body, and ignored my grandma's warnings that my pale skin was just not tough enough for the sun's powerful rays -- I would have basked in joy over headlines now surfacing in the media. They go something like this: the sun may actually fight skin cancer instead of causing it.

According to a team of scientists at the University of New Mexico's Cancer Research and Treatment Center, a little bit of ultraviolet B light is enough to stimulate a vitamin D immune response in the skin -- but it's not enough to boost skin cancer risk.

It's still true that sunlight is the main cause of skin cancer. But limiting exposure is the key to preventing the disease -- and for promoting bone health and perhaps preventing colon cancer too.

Researchers, whose findings are published in the March issue of
Nature Immunology, suggest staying out of the sun for now -- because they don't yet know what constitutes a little bit when it comes to UVB rays.

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